Home Categories Pharmaceutical intermediates SB-497115-GR
M5571035

SB-497115-GR , 99% , 496775-62-3

CAS NO.:496775-62-3

Empirical Formula: C27H29N5O5

Molecular Weight: 503.56

MDL number: MFCD22380664

EINECS: 629-876-8

Pack Size Price Stock Quantity
1mg RMB352.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMSO:56.33(Max Conc. mg/mL);99.76(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);1.77(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.44(Max Conc. mM)
Ethanol:0.1(Max Conc. mg/mL);0.18(Max Conc. mM)
form  Powder
Stability: Hygroscopic
InChIKey LQQUHOUXABUDJA-OUFJFOJPSA-N
SMILES C(N)CO.O=C1/C(/C(C)=NN1C1C=CC(C)=C(C)C=1)=N\NC1C=CC=C(C2C=CC=C(C(=O)O)C=2)C=1O

Description and Uses

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough.Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.

Treatment of chemotherapy-induced thrombocytopenia and treatment of immune thrombocytopenic purpura.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H412
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P273-P501

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