M5571035
SB-497115-GR , 99% , 496775-62-3
CAS NO.:496775-62-3
Empirical Formula: C27H29N5O5
Molecular Weight: 503.56
MDL number: MFCD22380664
EINECS: 629-876-8
Pack Size | Price | Stock | Quantity |
1mg | RMB352.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | DMSO:56.33(Max Conc. mg/mL);99.76(Max Conc. mM) DMF:1.0(Max Conc. mg/mL);1.77(Max Conc. mM) DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.44(Max Conc. mM) Ethanol:0.1(Max Conc. mg/mL);0.18(Max Conc. mM) |
form | Powder |
Stability: | Hygroscopic |
InChIKey | LQQUHOUXABUDJA-OUFJFOJPSA-N |
SMILES | C(N)CO.O=C1/C(/C(C)=NN1C1C=CC(C)=C(C)C=1)=N\NC1C=CC=C(C2C=CC=C(C(=O)O)C=2)C=1O |
Description and Uses
Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough.Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.
Treatment of chemotherapy-induced thrombocytopenia and treatment of immune thrombocytopenic purpura.
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H319-H412 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P273-P501 |