Home Categories Biochemical Engineering [Sar9,Met(O2)11]-SubstanceP,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2?
M5525335

[Sar9,Met(O2)11]-SubstanceP,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2? , >98% , 110880-55-2

Synonym(s):
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2

CAS NO.:110880-55-2

Empirical Formula: C64H100N18O15S

Molecular Weight: 1393.66

MDL number: MFCD00076787

Pack Size Price Stock Quantity
5mg RMB5106.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Density  1.43±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  H2O : 50 mg/mL (35.88 mM; Need ultrasonic)
pka 13.31±0.20(Predicted)
form  Lyophilized solid.
color  White to off-white
Water Solubility  Soluble to 1 mg/ml in water
Sequence H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2

Description and Uses

[Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4).

Safety

WGK Germany  3

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