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M4785953

ALPHA-SOLANINE , 98% , 20562-02-1

Synonym(s):
alpha-Solanine

CAS NO.:20562-02-1

Empirical Formula: C45H73NO15

Molecular Weight: 868.07

MDL number: MFCD00077873

EINECS: 243-879-8

Pack Size Price Stock Quantity
1mg RMB504.00 In Stock
5mg RMB2158.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 285℃ (dec.)
Boiling point: 780.78°C (rough estimate)
Density  1.40±0.1 g/cm3 (20 ºC 760 Torr)
refractive index  1.5280 (estimate)
storage temp.  −20°C
solubility  Methanol (Slightly, Heated), Pyridine (Slightly, Sonicated), Water (Slightly, Heated)
form  Solid
pka 6.66(at 15℃)
color  White to Off-White
Water Solubility  26.04mg/L(15 ºC)
Merck  13,8779
BRN  77607
InChIKey ZGVSETXHNHBTRK-MUEWWJAYNA-N
LogP 5.670 (est)

Description and Uses

This steroidal alkaloid is present in several Solanum species including S. nigrum, S. Iycopersicum (tomato) and S. tuberosum (potato). The base crystallizes in slender needles and shrinks markedly at 235°C. It has [α]20D - 59.45° (pyridine) or - 42.16° (dilute HCl) and is readily soluble in hot EtOH, sparingly so in H20 and virtually insoluble in CHCl 3 or Et2 0. The salts are mostly amorphous although a crystalline hydrochloride has been prepared with m.p. 212°C (dec.). It is not affected by alkalies but mineral acids hydrolyze it to solanidine (q.v.) and one mole each of dextrose, galactose and rhamnose.
Pharmacologically, the alkaloid is a protoplasmic poison and a powerful haemolytic. Poisoning by potatoes sometimes occurs although the results are not usually fatal. The symptoms are nausea, headache, emesis and gastritis. With large doses parenchymatous nephritis and haemoglobinuria occurs with, at times, paralysis of the central nervous system and cardiac arrest. The alkaloid also possesses local irritant properties.

α-Solanine is produced as a by product in the synthesis of α-Chaconine. α-Chaconine is a glycoalkaloid displaying nerve toxin activity. Potential antifungal activity.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  1-25-45-24/25
RIDADR  1544
WGK Germany  3
RTECS  WF0250000
10
HazardClass  6.1(b)
PackingGroup  III
HS Code  29399990
Hazardous Substances Data 20562-02-1(Hazardous Substances Data)

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