Thioridazinesolution , 1.0?mg/mLinmethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant? , 50-52-2

Synonym(s):
10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine

CAS NO.：50-52-2

Empirical Formula: C21H26N2S2

Molecular Weight: 370.57

MDL number: MFCD00242875

EINECS: 200-044-2

PRODUCT Properties

• Melting point: 72-74°
• Boiling point: bp0.02 230°
• Density: 1.1693 (rough estimate)
• refractive index: 1.5800 (estimate)
• Flash point: 9℃
• storage temp.: Sealed in dry,Room Temperature
• solubility: Practically insoluble in water, very soluble in methylene chloride, freely soluble in methanol, soluble in ethanol (96 per cent).
• pka: 9.5(at 25℃)
• Water Solubility: 1.113mg/L(22.5 ºC)
• NIST Chemistry Reference: 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-(50-52-2)

Description and Uses

An antipsychotic drug of the phenothiazine class. It is of particular interest because of its “atypical” properties, some of which may be due to its extensive bioconversion to active metabolites. The therapeutic and side effects of thioridazine and its metabolites involve blockade of brain dopamine receptors, but also actions mediated via blockage of muscarininc cholinergic and α-adrenergic receptors.

Mellaril(Novartis).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: F,T
• Risk Statements: 11-23/24/25-39/23/24/25-52/53
• Safety Statements: 16-36/37-45-61
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• HS Code: 2934302300
• Hazardous Substances Data: 50-52-2(Hazardous Substances Data)
• Toxicity: LD50 orally in rats: 995 ±39 mg/kg (Goldenthal)