M4356853
D-Methorphanhydrobromide , 125-69-9
Synonym(s):
(9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide;Dextromethorphan hydrobromide monohydrate
CAS NO.：125-69-9
Empirical Formula: C18H26BrNO
Molecular Weight: 352.31
MDL number: MFCD00269810
EINECS: 204-750-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 125-127℃ |
| alpha | D20 +27.6° (c = 1.5 in water) |
| pka | pKa 8.83(50%
aq EtOH) (Uncertain) |
| form | Solid |
| Water Solubility | Soluble in water (40 mM), and alcohol (1:10). |
Description and Uses
It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well. It is used as a pharmaceutical raw material.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312a-P330-P501a |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36/37 |
| RIDADR | 3249 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | cat,LD50,intravenous,19800ug/kg (19.8mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEASENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE,Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1207, 1972. |
