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M4050735

Mirodenafil , 98% , 862189-95-5

CAS NO.:862189-95-5

Empirical Formula: C26H37N5O5S

Molecular Weight: 531.67

MDL number: MFCD09954134

EINECS: 1533716-785-6

Pack Size Price Stock Quantity
5mg RMB2968.00 In Stock
10mg RMB4240.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 730.4±70.0 °C(Predicted)
Density  1.33
storage temp.  Store at -20°C
solubility  Soluble in DMSO
form  Powder
pka 14.96±0.10(Predicted)
color  White to off-white

Description and Uses

Mirodenafil (Mvix), a second-generation PDE5i, was launched in Korea in November 2007, and its orally dissolving film (Mvix S) was launched in December 2011. The product is available in tablet formulation or orally dissolving film of 50 and 100 mg. Mirodenafil has been approved only in Korea. Its pharmacokinetic profiles include a Tmax of 1.25 h, T1/2 of 2.5 h, and a IC50 for PDE5 of 0.34 nmol/L, which would confer a biochemical property of relatively high affinity (potency) for PDE5. While the pharmacokinetic profile is similar to that of sildenafil, mirodenafil appears to be 10 times more selective for PDE5 than sildenafil.

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