M4050735
Mirodenafil , 98% , 862189-95-5
CAS NO.:862189-95-5
Empirical Formula: C26H37N5O5S
Molecular Weight: 531.67
MDL number: MFCD09954134
EINECS: 1533716-785-6
Pack Size | Price | Stock | Quantity |
5mg | RMB2968.00 | In Stock |
|
10mg | RMB4240.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 730.4±70.0 °C(Predicted) |
Density | 1.33 |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | Powder |
pka | 14.96±0.10(Predicted) |
color | White to off-white |
Description and Uses
Mirodenafil (Mvix), a second-generation PDE5i, was launched in Korea in November 2007, and its orally dissolving film (Mvix S) was launched in December 2011. The product is available in tablet formulation or orally dissolving film of 50 and 100 mg. Mirodenafil has been approved only in Korea. Its pharmacokinetic profiles include a Tmax of 1.25 h, T1/2 of 2.5 h, and a IC50 for PDE5 of 0.34 nmol/L, which would confer a biochemical property of relatively high affinity (potency) for PDE5. While the pharmacokinetic profile is similar to that of sildenafil, mirodenafil appears to be 10 times more selective for PDE5 than sildenafil.