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M3764157

PD180970 , ≥98% , 287204-45-9

Synonym(s):
6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one;PF-1515965

CAS NO.:287204-45-9

Empirical Formula: C21H15Cl2FN4O

Molecular Weight: 429.27

MDL number: MFCD10565929

Pack Size Price Stock Quantity
10mg RMB2400.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 590.6±60.0 °C(Predicted)
Density  1.449±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: >20mg/mL
pka 3.02±0.20(Predicted)
form  A solid
color  yellow

Description and Uses

PD 180970 is an ATP-competitive inhibitor of p210 tyrosine kinase which selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H413
Precautionary statements  P273-P301+P310+P330
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

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