PRODUCT Properties
| Melting point: | 88-90℃ |
| Boiling point: | 476.6±45.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM) DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM) Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM) |
| pka | 14.43±0.40(Predicted) |
| form | White to off-white solid. |
| color | Off-white to light yellow |
| LogP | 3.380 (est) |
Description and Uses
Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.
