M3462935
Lomibuvir(VX-222,VCH-222) , 99% , 1026785-59-0
CAS NO.：1026785-59-0
Empirical Formula: C25H35NO4S
Molecular Weight: 445.61
MDL number: MFCD18089858
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB504.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 640.5±55.0 °C(Predicted) |
| Density | 1.21 |
| storage temp. | Store at -20°C |
| solubility | ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH |
| form | solid |
| pka | 3.67±0.10(Predicted) |
Description and Uses
Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).
VX-222, s a novel, potent and selective inhibitor of HCV polymerase .
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
