M3454857
GanoderenicacidA , ≥98% , 100665-40-5
Pack Size | Price | Stock | Quantity |
1mg | RMB960.00 | In Stock |
|
5mg | RMB2400.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 700.3±60.0 °C(Predicted) |
Density | 1.24±0.1 g/cm3(Predicted) |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Powder |
pka | 4.65±0.23(Predicted) |
color | White to off-white |
Description and Uses
Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities. It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes). Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 μg/ml.