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M2811035

GanoderenicacidD , 96% , 100665-43-8

CAS NO.:100665-43-8

Empirical Formula: C30H40O7

Molecular Weight: 512.634

MDL number:

Pack Size Price Stock Quantity
5mg RMB1152.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 218-220℃
Boiling point: 702.3±60.0 °C(Predicted)
Density  1.24±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 4.63±0.23(Predicted)
color  White to off-white

Description and Uses

Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. It inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. It also induces HeLa human cervical carcinoma apoptosis.

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