M2661435
Foretinib(GSK1363089) , ≥98% , 849217-64-7
CAS NO.：849217-64-7
Empirical Formula: C34H34F2N4O6
Molecular Weight: 632.65
MDL number: MFCD22379992
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB605.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >98°C (dec.) |
| Boiling point: | 828.5±65.0 °C(Predicted) |
| Density | 1.372 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Ethanol (Slightly) |
| form | Yellow powder. |
| pka | 13.14±0.70(Predicted) |
| color | Pale Yellow to Yellow |
Description and Uses
Foretinib is a multikinase inhibitor that targets MET and VEGFR2 and also exhibits an inhibitory effect against KIT, Flt-3, PDGFRb, and Tie-2.
XL880 (GSK1363089, EXEL-2880) is an ATP-competitive inhibitor of MET and KDR with IC50 of 0.4 nM and 0.9 nM, respectively.
Safety
| Symbol(GHS) |   GHS08,GHS07 |
| Signal word | Warning |
| Hazard statements | H373-H302 |
| Precautionary statements | P260-P314-P501-P264-P270-P301+P312-P330-P501 |
