M0919135
Carvedilolmetabolite4-HydroxyphenylCarvedilol , 98% , 142227-49-4
Synonym(s):
4′-Hydroxy carvedilol;4′-Hydroxyphenyl carvedilol;4′-OH carvedilol;4′OH-CVD;4-(2-(3-(9H-carbazol-4-yloxy)-2-hydroxypropylamino)ethoxy)-3-methoxyphenol
| Pack Size | Price | Stock | Quantity |
| 2mg | RMB1459.20 | In Stock |
|
| 5mg | RMB2280.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 163-165°C |
| Boiling point: | 702.0±60.0 °C(Predicted) |
| Density | 1.305±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.94±0.20(Predicted) |
| color | White to Light Brown |
Description and Uses
4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.
Safety
| HS Code | 9999999999 |
