Carvedilol , ≥98%(HPLC) , 72956-09-3

Synonym(s):
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol;BM-14190;Carvedilol

CAS NO.：72956-09-3

Empirical Formula: C24H26N2O4

Molecular Weight: 406.47

MDL number: MFCD00864692

EINECS: 1308068-626-2

PRODUCT Properties

• Melting point: 113-117°C
• Boiling point: 655.2±55.0 °C(Predicted)
• Density: 1.250±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: >20mg/mL
• pka: 13.90±0.20(Predicted)
• form: solid
• color: white to off-white
• Water Solubility: 449.2ug/L(22.5 ºC)
• Merck: 14,1873
• CAS DataBase Reference: 72956-09-3(CAS DataBase Reference)

Description and Uses

Carvedilol is a vasodilating beta-blocker useful in the treatment of hypertension and angina pectoris. In addition to lowering blood pressure, carvedilol decreases total vascular resistance without the reflex tachycardia usually occurring with vasodilators. It is reported to be well tolerated with renal sparing effects.

Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H411
• Precautionary statements: P273-P391-P501
• Hazard Codes: N,Xn
• Risk Statements: 51/53-36/37/38-20/21/22
• Safety Statements: 61-36-26
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• RTECS: UA8670000
• HazardClass: IRRITANT
• PackingGroup: III
• HS Code: 2933995300
• Hazardous Substances Data: 72956-09-3(Hazardous Substances Data)
• Toxicity: LD50 oral in dog: > 1gm/kg