CTPB? , 98% , 586976-24-1

Synonym(s):
Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl;CTPB;CTPB (enzyme activator);CTPB (enzyme inhibitor);N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide

CAS NO.：586976-24-1

Empirical Formula: C31H43ClF3NO2

Molecular Weight: 554.13

MDL number: MFCD08702707

PRODUCT Properties

• Boiling point: 560.7±50.0 °C(Predicted)
• Density: 1.104±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO: soluble
• pka: 12.27±0.70(Predicted)
• form: White to off-white crystalline solid.
• color: white to off-white
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Description and Uses

CTPB (586976-24-1) is a selective activator of p300 HAT (histone acetyltransferase) selective over PCAF (p300 CPB-associated factor).1,2

CTPB is an amide derivative that selectively activates the histone acetyltransferase (HAT) p300, with maximal activation at 275 μM. It directly binds p300. CTPB does not alter PCAF HAT or histone deacetylase activity. It dose-dependently increases the acetylation of histones H3 and H4, with maximal effect at 200 μM.

Safety

• WGK Germany: 3