PRODUCT Properties
| Melting point: | approximate 152℃ |
| Boiling point: | 613.0±55.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 12.88±0.70(Predicted) |
| color | White to Off-White |
Description and Uses
Betamethasone butyrate propionate (BBP) was introduced in Japan as a topical antiinflammatory agent. It is a synthetic corticosteroid with strong antiinflammatory activity at the site of inflammation but without topical or systemic side effects. On paper disk granuloma in rats, BBP was shown to have higher degree of dissociation between antiinflammation efficacy and systemic side effects than other agents in this class. Antipyretic/analgesic properties have also been reported.
Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H373-H361-H362 |
| Precautionary statements | P260-P314-P501-P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313 |
