Home Categories Pharmaceutical intermediates Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
LN9111546

Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate , 97% , 175137-27-6

CAS NO.:175137-27-6

Empirical Formula: C7H4ClF3N2O2

Molecular Weight: 240.57

MDL number: MFCD00068146

Pack Size Price Stock Quantity
1g RMB503.20 In Stock
5g RMB1168.00 In Stock
25g RMB4365.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 253-254 °C
Boiling point: 76-78°C 0,5mm
Density  1.491
refractive index  n20/D1.468
Flash point: >110℃
storage temp.  2-8°C
pka -5.70±0.29(Predicted)
CAS DataBase Reference 175137-27-6(CAS DataBase Reference)

Description and Uses

Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22-22
Safety Statements  26-36/37/39-23-51-24/25-22
RIDADR  UN 2810 6.1 / PGIII
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933599590

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