LN8036652
1802913-21-8
| Pack Size | Price | Stock | Quantity |
| 1g | RMB9704.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 574.5±50.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| solubility | Soluble in DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
Description and Uses
TCO-PEG4-acid is a click chemistry linker containing a TCO (trans-cycloctene) and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC. , TCO reagent is highly reactive with tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-DA reaction. The hydrophilic PEG spacer increases solubility in aqueous media.
TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
