(E)-Cyclooct-4-en-1-yl(2,5-dioxopyrrolidin-1-yl)carbonate , 95%rel-(1R-4E-pR)-equatorial , 1191901-33-3
Synonym(s):
(E)-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid;trans-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl carbonate;TCO-N-hydroxysuccinimidyl carbonate;TCO-carbonate;TCO-NHS
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB1528.80 | In Stock |
|
| 50mg | RMB2439.20 | In Stock |
|
| 100mg | RMB3900.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 90-105°C |
| Boiling point: | 369.1±45.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
| InChI | InChI=1S/C13H17NO5/c15-11-8-9-12(16)14(11)19-13(17)18-10-6-4-2-1-3-5-7-10/h1-2,10H,3-9H2/b2-1+ |
| InChIKey | OUGQJOKGFAIFAQ-OWOJBTEDSA-N |
| SMILES | C(ON1C(=O)CCC1=O)(=O)OC1CCCC=CCC1 |t:16| |
Description and Uses
TCO-NHS Ester is an popular reagent to label amine-containing compound or biomolecule, TCOI enable fast click chemistry with tetrazine.
Succinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.
Safety
| WGK Germany | 3 |
