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LN7488552

97% , 851067-56-6

CAS NO.:851067-56-6

Empirical Formula: C22H26BrN7O

Molecular Weight: 484.39

MDL number:

Pack Size Price Stock Quantity
50mg RMB640.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 682.2±65.0 °C(Predicted)
Density  1.495±0.06 g/cm3(Predicted)
solubility  Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated)
pka 8.66±0.10(Predicted)
form  Solid
color  Off-White to Yellow

Description and Uses

6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

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