LN7283046
α-Amanitin , 90% , 23109-05-9
CAS NO.：23109-05-9
Empirical Formula: C39H54N10O14S
Molecular Weight: 918.98
MDL number: MFCD00215842
EINECS: 245-432-2
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB5332.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 254-255 °C(lit.) |
| alpha | D20 +191° |
| Boiling point: | 1622.2±65.0 °C(Predicted) |
| Density | 1.1626 (rough estimate) |
| refractive index | 1.7400 (estimate) |
| storage temp. | −20°C |
| solubility | H2O: 1.0 mg/mL |
| form | powder |
| pka | 9.63±0.70(Predicted) |
| color | white to light yellow |
| optical activity | +19120 (H2O) |
| biological source | Amanita phalloides |
| Water Solubility | Soluble to 5 mM in ethanol and to 5 mM in water |
| ε(extinction coefficient) | 13,500 at 310nm in H2O at 1M |
| Merck | 13,370 |
| BRN | 1071138 |
| InChIKey | CIORWBWIBBPXCG-PWKRRBCNNA-N |
Description and Uses
α-Amanitin has been used:
- for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay
- to induce nephrotoxicity in mice renal tissues
- to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300-H373 |
| Precautionary statements | P260-P264-P270-P301+P310-P314-P405 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28-33-26/28 |
| Safety Statements | 36/37/39-45-36/37-28 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | BD6195000 |
| F | 8-10-18-21 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| HS Code | 2934999090 |
| Hazardous Substances Data | 23109-05-9(Hazardous Substances Data) |
| Toxicity | LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland) |
