12(S)-HpEPE(solutioninethanol) , ≥98% , 103239-14-1

CAS NO.：103239-14-1

Empirical Formula: C20H30O4

Molecular Weight: 334.45

MDL number: MFCD00065835

PRODUCT Properties

• storage temp.: Store at -20°C
• solubility: 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Description and Uses

12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE (Catalog No. 44570).

12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells[1].

Safety

• Symbol(GHS): GHS02
• Signal word: Danger