LN6483446
HerbimycinAfromStreptomyceshygroscopicus , 95% , 70563-58-5
Synonym(s):
Herbimycin A, Streptomyces sp. - CAS 70563-58-5 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 100ug | RMB1880.00 | In Stock |
|
| 500ug | RMB5374.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 229-231 °C |
| Boiling point: | 752℃ |
| Density | 1.19±0.1 g/cm3(Predicted) |
| Flash point: | >110°(230°F) |
| storage temp. | −20°C |
| solubility | DMSO: 7.5 mg/mL DMSO stock solution can be diluted in phosphate buffered saline. The ratio of buffer:DMSO should be greater than 500:1. |
| pka | 8.56±0.70(Predicted) |
| form | powder |
| color | yellow |
| Sensitive | Light Sensitive & Hygroscopic |
| BRN | 4834067 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Description and Uses
Herbimycin A (70563-58-5) is an ansamycin antibiotic. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB2.1,2 Herbimycin A reverts tyrosine kinase-induced oncogenic transformation without direct inhibition of phosphorylation activity.1 Inhibits angiogenesis in a rat retinopathy model.3
Herbimycin A is an inhibitor of c-Abl, HSP 90, c-Src, c-Yes, Fes, and Ros. It is a COVID19-related research product.
Safety
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| RTECS | LX8930000 |
| F | 10-21 |
| HS Code | 29419000 |
