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LN6109047

Triptorelinacetate , 98% , 140194-24-7

CAS NO.:140194-24-7

Empirical Formula: C64H82N18O13.C2H4O2

Molecular Weight: 1371.52

MDL number:

Pack Size Price Stock Quantity
25mg RMB312.00 In Stock
100mg RMB880.00 In Stock
1g RMB4000.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

solubility  Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated), Water (Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic
InChIKey HPPONSCISKROOD-UXTGTKPXNA-N

Description and Uses

Triptorelin acetate (TA) is a GnRH agonist that was earlier used as a veterinary drug for a single fixed-time artificial insemination through the synchronised estrous cycle of weaned sows. The risk assessment was that the Food Safety Commission of Japan (FSCJ) concluded that TA is not likely to cause adverse effects on human health through dietary exposure. Because TA does not have genotoxicity relevant to human health and is degraded in the digestive tract, its oral bioavailability is low. TA is currently used for the treatment of central precocious puberty and assisted reproduction. Injectable TA alone or in combination with levonorgestrel intrauterine device is also used to treat endometrial atypical hyperplasia (EAH) . Combination therapy is more effective, improving patients' menstrual abnormalities, endometrial thickening and quality of life, and is safe.

Synthetic peptide agonist analog of LH-RH. Triptorelin acetate is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360

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