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LN4971753

Chlorfenapyr , 98% , 122453-73-0

Synonym(s):
4-Bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrol-3-carbonitrile

CAS NO.:122453-73-0

Empirical Formula: C15H11BrClF3N2O

Molecular Weight: 407.61

MDL number: MFCD01631152

Pack Size Price Stock Quantity
25G RMB1512.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 91-92°
Boiling point: 443.5±45.0 °C(Predicted)
Density  1.53±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
Water Solubility  Insoluble in water
solubility  DMSO: 250 mg/mL (613.33 mM)
pka -18.00±0.70(Predicted)
form  Solid
color  White to Almost white
BRN  6940152
InChI InChI=1S/C15H11BrClF3N2O/c1-2-23-8-22-13(9-3-5-10(17)6-4-9)11(7-21)12(16)14(22)15(18,19)20/h3-6H,2,8H2,1H3
InChIKey CWFOCCVIPCEQCK-UHFFFAOYSA-N
SMILES N1(COCC)C(C(F)(F)F)=C(Br)C(C#N)=C1C1=CC=C(Cl)C=C1

Description and Uses

Chlorfenapyr is a pyrrole pro-insecticide that is metabolized in vivo into CL 303268 by mixed function oxidases. Chlorfenapyr increases respiratory activity in German cockroaches when used at concentrations ranging from 1 to 10 μg per insect but has no effect on respiration in Sf9 cells when used at concentrations ranging from 1 to 100 μM and does not affect respiration in isolated rat liver mitochondria up to a concentration of 10 μM. Chlorfenapyr is active against a variety of insects including those susceptible and resistant to pyrethroid and organophosphate insecticides, including horn flies (H. irritans) as well as A. culicifacies and A. stephensi mosquitos that carry malaria (LC50s = 2-2.39% suspension impregnated on paper). Chlorfenapyr is lethal to rats with LD50 values of 441 and 1,152 mg/kg for male and female rats, respectively. Formulations containing chlorfenapyr have been used to control termites and in agriculture to control various insects.

Chlorfenapyr is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pes t control on cotton.

Safety

Symbol(GHS) 
GHS06,GHS09
Signal word  Danger
Hazard statements  H302-H331-H410
Precautionary statements  P261-P264-P270-P273-P301+P312-P304+P340+P311
Hazard Codes  T;N,N,T
Risk Statements  22-23-50/53
Safety Statements  13-36/37-45-60-61
RIDADR  UN 2811
WGK Germany  3
HS Code  2933.99.1701
Toxicity LD50 (single dose) in male, female rats (mg/kg): 223, 459 orally; in rabbits: >2000 dermally (Lovell); LC50 in Japanese carp: 0.5 ppm (Lovell)

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