LN4360148
Methyl3-Nitropropanoate , ≥95% , 20497-95-4
| Pack Size | Price | Stock | Quantity |
| 5g | RMB8160.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 68 °C/1 mmHg(lit.) |
| Density | 1.249 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.4350(lit.) |
| Flash point: | 110 °C |
| pka | 7.67±0.29(Predicted) |
Description and Uses
Methyl 3-Nitropropanoate is used to nitroaldol additions, condensation reactions, and Michael additions involving the NO2-substituted carbon; the α-carbonyl carbon in dilithionitronate enolates of the esters undergoes alkylations, double alkylations, and aldol and Michael additions; elimination of HNO2 from the products gives α,β- unsaturated esters with substituents in either the β- or the α-position, thus making the reagent a synthetic equivalent of acrylate anions with d3 or d2 reactivity; precursor to nitrile oxide for [3 + 2] cycloadditions; 3-nitropropanoyl chloride can be used for enolate acylation and five-membered ring annulation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
