TerritremA , ≥98% , 70407-19-1
| Pack Size | Price | Stock | Quantity |
| 500ug | RMB2296.00 | In Stock |
|
| 2.5mg | RMB8600.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| form | A solid |
Description and Uses
Territrem A is a mycotoxin originally isolated from A. terreus that irreversibly inhibits acetylcholinesterase (AChE; IC50 = 24 nM for the electric eel enzyme). It is toxic to mice, inducing tremors with a median tremulous dose of 0.31 mg/kg, and has an LD50 value of 17.6 mg/kg.
Territrem A is an α-pyrone tremorgenic mycotoxin first identified from an Aspergillus terreus strain by Ling and colleagues at Taiwan National University in 1979. Territrem A is a potent insecticide acting via irreversible inhibition of acetylcholinesterase (AChE). The binding mechanism is very different from typical irreversible AChE inhibitors like neostigmine and the organophospates.
