AbacavirCarboxylate , ≥98% , 384380-52-3

CAS NO.：384380-52-3

Empirical Formula: C14H16N6O2

Molecular Weight: 300.32

MDL number:

PRODUCT Properties

• Melting point: 208-210°C (dec.)
• storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• form: Solid
• color: Off-White to Pale Beige
• Stability: Hygroscopic

Description and Uses

Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir . It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.

Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).