Home Categories Pharmaceutical intermediates Levodropropizine
LN3378349

Levodropropizine , ≥98% , 99291-24-4

Synonym(s):
(2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol

CAS NO.:99291-24-4

Empirical Formula: C13H20N2O2

Molecular Weight: 236.31

MDL number: MFCD00866852

Pack Size Price Stock Quantity
50mg RMB640.00 In Stock
100mg RMB856.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 98-100°
alpha  D25 -10° (c = 1.0 in ethanol)
Boiling point: 412.7±34.0 °C(Predicted)
Density  1.168±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Acetonitrile (Slightly), Methanol (Slightly)
pka 14.21±0.20(Predicted)
color  White to Off-White

Description and Uses

Levodropropizine is an antitussive with antiinflammatory activity, the L-isomer of dropropizine. Compared with the racemate, levodropropizine is reported to have less sedative potential and better therapeutic index, while maintaining the the same efficacy levels as an antitussive and antiinflammatory.

R-Form of Dropropizine (D681495). (R)-(+)-Dropropizine is a cough suppressive phenylpiperazine derivative. (R)-(+)-Dropropizine is an antitussive and central sedative therapeutic agent.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Toxicity LD50 in mice, rats (mg/kg): 1287.2, 886.6 orally; 408.0, 401.3 i.p. (Borsa)

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