LN3166149
SteffimycinB , ≥98% , 54526-94-2
Pack Size | Price | Stock | Quantity |
1mg | RMB2932.00 | In Stock |
|
5mg | RMB9516.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 801.2±65.0 °C(Predicted) |
Density | 1.52±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
form | A lyophilisate |
pka | 5.09±0.70(Predicted) |
Description and Uses
Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp., with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher CpG base sequence specificity over the TpA step, similar to that of daunorubicin and nogalamycin. A close analogue was shown to be active against ras oncogene-expressed cells.