LN3007649
JX401 , ≥98% , 349087-34-9
Synonym(s):
N-(2-Methoxy-4-thiomethyl)benzoyl-4-benzylpiperidine;p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB3856.00 | In Stock |
|
| 50mg | RMB15256.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Store at RT |
| solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml). |
| form | Off-white solid |
| color | White |
| Stability: | Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
Description and Uses
JX401 (349087-34-9) is a potent, cell-permeable inhibitor of p38α (IC50 = 32 nM). No inhibition of p38β was observed at 10 μM.
JX-401 is a potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM). It does not inhibit the p38γ isoform. JX-401 is effective in mammalian cells, as it blocks the differentiation of myoblasts into myotubes.[Cayman Chemical]
