Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-L-lactoyl-Ser-Lys(DABCYL)-NH2 ammonium salt , ≥95% , 188530-20-3
CAS NO.：188530-20-3
Empirical Formula: C68H89N15O25S
Molecular Weight: 1548.58
MDL number: MFCD01318843
| Pack Size | Price | Stock | Quantity |
| 100ug | RMB2581.60 | In Stock |
|
| 250ug | RMB4175.20 | In Stock |
|
| 500ug | RMB6524.00 | In Stock |
|
| 1mg | RMB10643.20 | In Stock |
|
| 2mg | RMB17792.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Density | 1.49±0.1 g/cm3(Predicted) |
| pka | -0.26±0.40(Predicted) |
Description and Uses
Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm.)
