Lipstatin , 96829-59-3

CAS NO.：96829-59-3

Empirical Formula: C29H49NO5

Molecular Weight: 491.7

MDL number: MFCD09838128

PRODUCT Properties

• Boiling point: 627.4±55.0 °C(Predicted)
• Density: 0.993
• storage temp.: -20°C Freezer, Under Inert Atmosphere
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• pka: 14.57±0.23(Predicted)
• form: Oil
• color: Clear Colorless to Light Yellow

Description and Uses

Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338