LN-825492
DOXYLAMINE , 99% , 469-21-6
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 25°C |
| Boiling point: | bp0.5 137-141° |
| Density | 1.0023 (rough estimate) |
| refractive index | 1.5486 (estimate) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | pKa 9.20(H2O
t = 25
c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain) |
| color | Colourless |
| Stability: | Temperature Sensitive |
| EPA Substance Registry System | Doxylamine (469-21-6) |
Description and Uses
Antihistaminic.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| Hazardous Substances Data | 469-21-6(Hazardous Substances Data) |
| Toxicity | An antihistamine that formerly was used in pregnant women for antihistaminic and sedative properties. Although it has excellent sedative properties, it has been implicated in teratogenesis and in causing neurobehavioral toxicity and is therefore no longer used |
