LN-733527
althiomycin , 12656-40-5
CAS NO.：12656-40-5
Empirical Formula: C16H17N5O6S2
Molecular Weight: 439.47
MDL number: MFCD01681520
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 172-174 °C (decomp) |
| Density | 1.72±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 9.67±0.10(Predicted) |
| form | A crystalline solid |
Description and Uses
Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL.
