LN-711632
D-GLUCOHEPTONO-1,4-LACTONE , 98% , 60046-25-5
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 152-155 °C(lit.) |
| Boiling point: | 267.35°C (rough estimate) |
| Density | 1.3807 (rough estimate) |
| refractive index | 1.4455 (estimate) |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Water (Slightly) |
| pka | 12.05±0.60(Predicted) |
| form | Solid |
| color | White to Pale Beige |
Description and Uses
It is used in the synthesis of Howiinol A and its analogs. Howiinol A was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| WGK Germany | 3 |
| HS Code | 2932209090 |
