LN-564032
Bizelesin , NLT 98% , 129655-21-6
Update time: 2023-04-23
PRODUCT Properties
| Density | 1.604±0.06 g/cm3(Predicted) |
| pka | 10.06±0.40(Predicted) |
| form | Solid |
| color | Off-white to yellow |
Description and Uses
As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both si ngle-strand lesions and double-strand DNA cross-links. liferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).
