LN-541529
4-Hydroxy Duloxetine b-D-Glucuronide , 95% , 741693-83-4
CAS NO.:741693-83-4
Empirical Formula: C24H27NO8S
Molecular Weight: 489.542
MDL number: MFCD09952222
Update time: 2023-04-23
PRODUCT Properties
Melting point: | >190°C (dec.) |
Boiling point: | 781.8±60.0 °C(Predicted) |
Density | 1.450±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
pka | 2.76±0.70(Predicted) |
form | Solid |
color | White to Brown |
Stability: | Hygroscopic |
Description and Uses
4-Hydroxy Duloxetine Glucuronide is a derivative of 4-Hydroxy Duloxetine (H941800), a major metabolite of Duloxetine (D721000), which acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate.