LN-527431
lactoquinomycin B , 101342-94-3
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 149-152 °C (decomp) |
| Boiling point: | 736.8±60.0 °C(Predicted) |
| Density | 1.52±0.1 g/cm3(Predicted) |
| pka | 6.15±0.40(Predicted) |
Description and Uses
Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively[1].
