PAGOCLONE , 99.99% , 133737-32-3

CAS NO.：133737-32-3

Empirical Formula: C23H22ClN3O2

Molecular Weight: 407.89

MDL number: MFCD00864700

EINECS: 225-799-5

PRODUCT Properties

• Boiling point: 582.1±50.0 °C(Predicted)
• Density: 1.273±0.06 g/cm3(Predicted)
• pka: 1.62±0.30(Predicted)
• form: Solid
• color: White to off-white
• InChI: InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
• InChIKey: HIUPRQPBWVEQJJ-UHFFFAOYSA-N
• SMILES: C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2

Description and Uses

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

Anti-anxiety agent.