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A7130312

Risperidone , ≥98% , 106266-06-2

Synonym(s):
R 64,766;Risperidone

CAS NO.:106266-06-2

Empirical Formula: C23H27FN4O2

Molecular Weight: 410.48

MDL number: MFCD00274576

EINECS: 600-733-1

Pack Size Price Stock Quantity
500mg RMB23.20 In Stock
1g RMB45.60 In Stock
5G RMB173.60 In Stock
25G RMB729.60 In Stock
100G RMB2903.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 170°C
Boiling point: 572.4±60.0 °C(Predicted)
Density  1.38±0.1 g/cm3(Predicted)
Flash point: 9℃
storage temp.  2-8°C
solubility  DMSO: ≥5mg/mL
pka pKa 8.3 (Uncertain)
form  powder
color  white to off-white
Water Solubility  44.74mg/L(25 ºC)
Merck  14,8233
BCS Class 2
CAS DataBase Reference 106266-06-2(CAS DataBase Reference)

Description and Uses

Risperidone is a novel antipsychotic introduced for the treatment of acute and chronic schizophrenia. It has a balanced serotonin 5-HT2 and dopamine D2 receptor antagonist activity. While the anti-D2 activity may relate to the antipsychotic potency of neuroleptic agents, an antidepressive efficacy of substances with anti-5-HT2 activity has been suggested. Risperidone, therefore, has therapeutic action on both positive and negative symptoms of schizophrenia and produces significantly fewer side effects especially extrapyramidal symptoms compared with commonly used pure D2 antagonist antipsychotics. It also has potential for management of alcohol withdrawal and cocaine addiction.

For the treatment of schizophrenia in adults and in adolescents, ages 13 to 17, and for the short-term treatment of manic or mixed episodes of bipolar I disorder in children and adolescents ages 10 to 17. May also be used to manage symptoms of inappropria

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T,F
Risk Statements  25-39/23/24/25-23/24/25-11
Safety Statements  28-36-45-36/37-16
RIDADR  3249
WGK Germany  3
RTECS  UV1164800
HazardClass  6.1(a)
PackingGroup  II
HS Code  29333990
Hazardous Substances Data 106266-06-2(Hazardous Substances Data)
Toxicity LD50 in male, female mice, rats, dogs (mg/kg): 29.7, 26.9, 34.3, 35.4, 14.1, 18.3 i.v.; 82.1, 63.1, 113, 56.6, 18.3, 18.3 orally (Janssen, 1988)

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