LN-434216
Cloxacillin , 99% , 61-72-3
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 689.7±55.0 °C(Predicted) |
| Density | 1.2954 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| pka | pKa 2.70±0.07(H2O t=35.0 c=0.0025) (Uncertain) |
| InChIKey | LQOLIRLGBULYKD-JKIFEVAISA-N |
| SMILES | N12[C@@]([H])([C@H](NC(C3=C(C)ON=C3C3=CC=CC=C3Cl)=O)C1=O)SC(C)(C)[C@@H]2C(O)=O |
Description and Uses
Cloxacillin induced contact dermatitis in a pharmaceutical factory worker with positive reactions to ampicillin but not to penicillin. The chemical formula of this is 3-o-chlorophenyl-5-methyl-4-isoxazolyl penicillin (Knudsen et al., 1962); this differs from oxacillin only by an additional chlorine atom.
Cloxacillin is a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. It is used to treat a wide variety of bacterial infections.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
