LN-393716
Eplerenone EP Impurity B , 90%+ , 192704-82-8
Update time: 2023-04-23
PRODUCT Properties
Boiling point: | 592.6±50.0 °C(Predicted) |
Density | 1.30±0.1 g/cm3(Predicted) |
solubility | Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Description and Uses
(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.