LN-085926
Eplerenone EP Impurity A , 98%; CRLIU 041 , 209253-67-8
Update time: 2023-04-23
PRODUCT Properties
Boiling point: | 632.9±55.0 °C(Predicted) |
Density | 1.31±0.1 g/cm3(Predicted) |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Description and Uses
(7a,17a)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.