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LN-085926

Eplerenone EP Impurity A , 98%; CRLIU 041 , 209253-67-8

CAS NO.:209253-67-8

Empirical Formula: C23H28O5

Molecular Weight: 384.47

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Boiling point: 632.9±55.0 °C(Predicted)
Density  1.31±0.1 g/cm3(Predicted)
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White

Description and Uses

(7a,17a)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

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