LN-240932
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT , 99% by HPLC , 142754-28-7
CAS NO.：142754-28-7
Empirical Formula: C10H10ClN5NaO5PS
Molecular Weight: 401.7
MDL number: MFCD03452651
Update time: 2023-04-23
Description and Uses
Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of human leukemia cell HL-60 and colon cancer cell LS-174T, with IC50 of 8-100 μM. Sp-8-Cl-cAMPS activates the protein kinases cAKI and cAKII, with Ka of 0.25 and 3.2 μM[1].
