LN-166132
Tilisolol HCl , NLT 98% , 62774-96-3
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 203-205° |
| storage temp. | Sealed in dry,Room Temperature |
Description and Uses
Tilisolol hydrochloride is a long acting vasodilating beta-blocker useful in the treatment of hypertension and angina. It is also reported to have antiarrhythmic properties. Due to its relatively long half-life, tilisolol hydrochloride is suitable for once a day dosing. It is currently being investigated as an antiglaucoma agent.
Safety
| Toxicity | LD50 in male, female mice and rats (mg/kg): 1393, 1290, 145, 188 orally; 1219, 1245, 176, 169 s.c.; 578, 557, 39.5, 29.2 i.p.; 74.3, 104.7, 75.8, 38.1 i.v. (Kawase) |
