LN-154132
2-([1-(3-[[3-(DIMETHYL(3-[4-[(E)-(3-METHYL-1,3-BENZOXAZOL-3-IUM-2-YL)METHYLIDENE]-1(4H)-QUINOLINYL]PROPYL)AMMONIO)PROPYL](DIMETHYL)AMMONIO]PROPYL)-4(1H)-QUINOLINYLIDENE]METHYL)-3-METHYL-1,3-BENZOXAZOL-3-IUM TETRAIODIDE , 98% , 143413-85-8
CAS NO.:143413-85-8
Empirical Formula: C49H58IN6O2+3
Molecular Weight: 889.95
MDL number: MFCD07433935
Update time: 2023-04-23
PRODUCT Properties
Melting point: | >250 ℃ |
solubility | Soluble in dimethyl sulfoxide, water |
form | powder |
color | Orange-red |
λmax | 491 nm |
Biological Applications | Nucleic acid hybridization; nucleic acid sequencing; detecting nucleic acids,cells,human papilloma virus (HPV),pathogens,spores,cancer cells,stress biomarkers,viruses |
Description and Uses
Thiazole orange dimer YOYO 1 is a green fluorescent dye used for DNA staining. It belongs to the monomethine cyanine dye family and is a tetracationic homodimer of oxazole yellow (abbreviated as YO, hence the name YOYO), usually provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) has a very low fluorescence quantum yield, but after binding to double-stranded DNA through diintercalation, the fluorescence intensity is increased by 3200 times (λmax 489 nm; λmax 509 nm).