LN-154012
Plitidepsin , 97% , 137219-37-5
CAS NO.：137219-37-5
Empirical Formula: C57H87N7O15
Molecular Weight: 1110.34
MDL number: MFCD00947315
| Pack Size | Price | Stock | Quantity |
| 1mg | USD998.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 152-160° |
| alpha | D -95.9° (c = 1.8 in CHCl3) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| pka | 11.28±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | UUSZLLQJYRSZIS-NIORUGPLNA-N |
Description and Uses
Plitidepsin is a cyclic depsipeptide that was first isolated from a Mediterranean marine tunicate (Aplidium albicans) and, at present, is manufactured by total synthesis and commercialized as Aplidin?. Its antitumor activity, observed in preclinical in vitro and in vivo studies has prompted numerous clinical trials to be conducted over the last 17 years, alone or in combination with other anticancer agents.
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225-H302+H312+H332-H319 |
| Precautionary statements | P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P321-P330-P362+P364-P337+P313-P370+P378-P403+P235-P501 |
