LN-097516
10-formyldihydrofolate , 90%+ , 28459-40-7
Update time: 2023-04-23
PRODUCT Properties
| Density | 1.67±0.1 g/cm3(Predicted) |
| solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
| pka | 3.38±0.10(Predicted) |
| form | Solid |
| color | Orange to Very Dark Brown |
| Stability: | Hygroscopic, Temperature Sensitive |
Description and Uses
10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501 |
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