Home Categories 5-epi EMtricitabine
LN-083634

5-epi EMtricitabine , 0.95 , 145986-26-1

CAS NO.:145986-26-1

Empirical Formula: C8H10FN3O3S

Molecular Weight: 247.25

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Melting point: >166°C (dec.)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  White to Pale Beige
Stability: Hygroscopic

Description and Uses

5-epi Emtricitabine is an epimer of Emtricitabine (E525000), a nucleoside reverse transcriptase inhibitor approved for treatment of human immunodeficiency virus (HIV) 1, and also has antagonistic activity against the hepatitis B virus. 5-epi Emtricitabine is also used as a reagent for the synthesis of β-L-(2R,5S)- and α-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential HIV agents.

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